Thursday, April 26, 2012

Sprint reports Q1 2012 results: 1.5 million iPhone sales but a $255 million operating loss

Sprint reports Q1 2012 financials, 1.5 million iPhone sales but a $255 million loss

Sprint Nextel has just deployed its Q1 2012 financials and it's a bit of a mixed bag, with a five percent net revenue growth over this time last year and a whopping 1.5 million sales of that iPhone it paid so dearly for -- twice as many as it sold last quarter and, of those, 44 percent were new subscribers. That helped to drive an overall postpaid subscriber growth of 263,000 but, despite some good news, the company is still suffering a $255 million operating loss and a $863 million net loss. Sprint reaffirmed its LTE plans, a pilot launch of six cities sometime in the middle of this year, with 12,000 sites going online before 2012 turns a year older. Will it be enough? Tune in next quarter to find out.

Sprint reports Q1 2012 results: 1.5 million iPhone sales but a $255 million operating loss originally appeared on Engadget on Wed, 25 Apr 2012 07:25:00 EDT. Please see our terms for use of feeds.

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NASA preps J-2X rocket engines for second round testing, SLS creeps closer to 2017 liftoff

Image

Forty-year old tech taking astronauts into space? Sadly, that's been the current state of our space program. But in the spirit of making one extra, giant leap for mankind, our nation's best and brightest aeronautic minds have been quietly working on a propulsion system designed to power the SLS and its Orion spacecraft payload deeper into the cosmos. NASA's been testing these next-gen J-2X rockets since last year, proving their ability to "[achieve] full flight-duration firing of 500 seconds" at sea-level and, now, in a series of second round testing, the engines will be put through their paces at high altitudes. The first of 16 planned tests are scheduled to kick off this Wednesday at the agency's Stennis Center in Mississippi and should run through to year-end. Check out the official presser after the break for a fuller breakdown of this evolution in galactic travel.

Continue reading NASA preps J-2X rocket engines for second round testing, SLS creeps closer to 2017 liftoff

NASA preps J-2X rocket engines for second round testing, SLS creeps closer to 2017 liftoff originally appeared on Engadget on Wed, 25 Apr 2012 04:38:00 EDT. Please see our terms for use of feeds.

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Netflix brought into the Sony Entertainment Network fold for British Bravia buffs

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Britons and citizens of the ROI! Sony's bringing Netflix to all Sony Entertainment Network-connected devices. It looks like Kaz Hirai's plan to "unify" the company and its media offerings is beginning to gain a little momentum. If you have a SEN-connected 2012 Bravia TV or Blu-ray player, then the app should be available soon -- although no-one seems to know precisely when. If you're on PS3, or in the States, then Netflix is old news, so don't bother with the press release after the break

Continue reading Netflix brought into the Sony Entertainment Network fold for British Bravia buffs

Netflix brought into the Sony Entertainment Network fold for British Bravia buffs originally appeared on Engadget on Wed, 25 Apr 2012 06:31:00 EDT. Please see our terms for use of feeds.

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Wednesday, April 25, 2012

Never Underestimate the Power of a Strong Title Sequence [Video]

An amazing opening-credit sequence can really immerse an audience, setting the tone for the entire film. PBS's Off Book series showcases the designers behind such films as Seven, Blue Valentine, and Mad Men. Watch the video to hear their approach to such a specific, but important, aspect of filmmaking. [YouTube / PBS va Laughing Squid] More »


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Growing Up Geek: Sarah Silbert

Welcome to Growing Up Geek, an ongoing feature where we take a look back at our youth and tell stories of growing up to be the nerds that we are. Today, we have our new reviews editor, Sarah Silbert.

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I'm not your textbook-case geek. On that authoritative dork-geek-nerd venn diagram, I sit undeniably closer to the nerd quadrant. I mean, a childhood defined by penning mini-zines, banging on the piano and filming countless movies in my garage hardly earned me a reputation as a precocious little techie. Sure, I liked computers and math -- and I, er, may have graphed the distribution of my Halloween candy once or twice, just for fun -- but my entryway into gadgets and geekdom was an overactive imagination.

Continue reading Growing Up Geek: Sarah Silbert

Growing Up Geek: Sarah Silbert originally appeared on Engadget on Wed, 25 Apr 2012 15:40:00 EDT. Please see our terms for use of feeds.

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MF Global and its Lessons about Threat in Foreign currency trading ...

Currency trading is actually a important part of the worldwide financial system to which people have entry by way of specific forex trading accounts. Use the guidelines beneath derived in the MF Worldwide bankruptcy illustration to be aware of how the company you deal with can contribute to your riskiness of forex investing.

The financial well-being of your companies you deal with impact the riskiness of the investment decision. Forex trading investors who made use of MF Worldwide missing their income due to the fact of your company?s bankruptcy. The cash in forex accounts is simply not insured in any technique to shield clients inside the event of the firm?s bankruptcy.

Just before you setup an account you can examine info inside the high-quality print that explains the danger to forex traders inside the event of business bankruptcy. The high-quality print may even clarify that commonly much more than one particular business is involved in forex transactions so people is often utilizing one particular company?s platform but there income can often be planning by way of one or more counter-parties.

Forex trading transactions have several individuals given that they entail shopping for and offering currencies. This implies that you may possibly imagine you might be managing one particular business when the truth is there may be a counter-party handling the majority of your transactions. For example, when you open up an account by using a well-known financial establishment and use their platform, you should keep reading to find out where your income actually finally ends up. Numerous of those firms only present a platform instead than conducting transactions.

MF Global?s boueux have been traced again ages. Federal government oversight usually is inadequate to catch a problem before it gets to be a disaster. The CFTC web-site features quite a lot of reassuring rules together with their power to go after companies that interact in business techniques that break the rules. Even so, as any specific appreciates that has dealt with federal government agencies, the lag time amongst the onset of the dilemma and any significant federal government action that can shield someone usually decreases specific protection obtainable from overseeing governmental authorities.

Consumers ought to carefully look at the value of the self-regulatory business just like the NFA. The NFA is employing new ?rules?? post-MF Worldwide mainly due to the fact ahead of the MF Worldwide bankruptcy there were no consumer-friendly warnings or steps taken from the NFA about MF Worldwide. Although people realize that membership We know that you are enjoying all that is offered about energy efficient windows cost. Sure, we know this is just one article, but take it from us when we tell you there is so much more to know. But be careful about dismissing anything too fast if at first glance it seems like it does not apply to you.

Everything is related in one way or another, and that is part of the beauty of it all. It is hardly ever a good idea to maintain a closed mind about anything, and that has served us very well. In the rest of our discussion, we will offer more information that will reinforce what you have already learned, and then you will be better equipped to understand. Try not to feel like you are going through information overload because, after all, this is stuff you can easily understand. inside the Countrywide Futures Association is voluntary, people ought to never ever depend on their forex investments currently being safeguarded by these kinds of self-regulators. Just like the federal government, the MF Worldwide condition signifies that reluctance to act on behalf of people expense people income.

Some of MF Worldwide creditors are finding some income although not forex traders. Forex trading traders will not be finding reimbursed inside the bankruptcy of MF Worldwide. Even though bankruptcy gives for spending off a variety of creditors, at the very least some quantity, forex traders will not be finding reimbursed. The danger of dropping your income inside the event a agency goes bankrupt is often a hundred % due to the fact creditors have priority according to their status and forex investors undoubtedly are a minimal priority legally to creating a claim.

Forex trading clients in Canada have been publicized given that they have been finding again a hundred % of their income from MF Worldwide. This does not alter the danger for forex traders inside the event an organization goes bankrupt due to the fact MF Worldwide Canada was a special entity which had not misplaced or mismanaged its income, and it had the cash to pay for its clients.

Forex trading money are held in non-segregated accounts. It truly is important to notice that MF Worldwide bought into real problems when it begun raiding investment decision income held in segregated accounts. Segregated accounts imply just that when it comes to income currently being expected to get held separately for that part of your business. Due to the fact forex money will not be held in segregated accounts, when a agency wants income to go over some other part of its business the forex money are part of the methods it takes advantage of.

It truly is well-known that better probability in financial transactions would make the possibility of better gains feasible. forex trading is dangerous to get a amount of factors like its susceptibility to your dangers of your companies you deal with. Use the guidelines above to contemplate the company you deal with in forex trading.

In mere seconds you can discover a few possibly shocking pieces of information concerning government job for pharmacist that we think you will love. It is incredibly simple to overlook the most useful information because it is spread out all over the web. It is just that people make honest slipups because they are misinformed, but we can help you avoid that pitfall, altogether.

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HTC EVO 4G LTE pre-order page goes live on Sprint's website, fanboy early birds rejoice

HTC EVO 4G LTE pre-order page goes live on Sprint's website, fanboy early birds rejoice

April's been kind to fans of Sprint's forthcoming HTC EVO 4G LTE, as it's brought us leaked pics of the handset and its ruby-red kickstand, proffered a video preview of it in action, and even gave a glimpse of how it's made. We also found out that pre-orders weren't set to start until May 7th, but Sprint's gone ahead and put the pre-order page up a bit early. See for yourself at the source link below, where forgetful Now Network customers can get Sprint to send them an email reminder to plunk down their hard-earned cash and reserve the new EVO in a couple weeks. Wouldn't want to forget and be among that second wave of owners, now would you?

[Thanks, Chris]

HTC EVO 4G LTE pre-order page goes live on Sprint's website, fanboy early birds rejoice originally appeared on Engadget on Mon, 23 Apr 2012 21:22:00 EDT. Please see our terms for use of feeds.

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Tuesday, April 24, 2012

Betwixt and Between

Betwixt and Between

The worlds we know are like islands on a sea. All you need to travel them is a sturdy vessel, and the will.

Owner:

Game Masters:

This topic is an Out Of Character part of the roleplay, ?Betwixt and Between?. Anything posted here will also show up there.

Topic Tags:

Forum for completely Out of Character (OOC) discussion, based around whatever is happening In Character (IC). Discuss plans, storylines, and events; Recruit for your roleplaying game, or find a GM for your playergroup.
This is the auto-generated OOC topic for the roleplay "Betwixt and Between"

You may edit this first post as you see fit.

A fragmented tale, eternally retold.
When darkness falls, two shall stand against it.
The crimson-haired girl and the beach born boy,
their fates intertwined, stand together.

Come my children and listen,
For time is all we have.

-Darkness on the Coast

User avatar
Beach-Born-Boy
Member for 0 years



Hi.. I submitted a character but it isn't finished yet and I don't have the time right now.

User avatar
jigokunoshinzo
Member for 0 years


While I am considering joining this RP, I'm a bit confused by this statement:

There are those who work with them even though they cannot use their weapons and these people are rewarded handsomely.

And yet there's a weapons section in the form. Are there certain parts where characters can't use their weapons?

User avatar
Pichu-Chan
Member for 2 years


There are different weapons that are more powerful for the leaders. These are the ones that the others can't use. Sorry if that's unclear but I'm just unsure how to put it.

User avatar
Beach-Born-Boy
Member for 0 years



Post a reply

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Wednesday, April 18, 2012

Eating 'Green' restore your Eyes

Eye plays an important role in our body system. This is the only medium, through which we can imagine our life on the basis of what we see is what we have with our true efforts. So it becomes our prime duty towards us to protect our eyes as on priority.
?
Maintaining hygiene practices of hands and body can give lots of benefits to protect eyes too. People should regularly consult some good eye doctors to update your eyes vision. It?s better to follow all the remedies which are being prescribed by your doctor every time without mis. An eye specialist may perform an eye surgery in Delhi for someone suffering from partial blindness or full blindness to restore their vision.

There can be certain healthy tips to be followed for maintaining eyes every day:
? ?Regular use of prescribed eye drops by your doctor.
? ?Keep wash your face with good anti bacterial soap or liquid wash.
? ?Minimum use of computer, TV or mobile phones because it harmful rays impact over the eyes.
? ?Take adequate sleep of at least 8 hours a day.
? ?Eat green and yellow fruits and vegetables as a good source of vitamin A and iron.

Both theses vitamins are meant to enhance eyes vision.

After using all these prior information, if you still feel any sort of discomfort in your eye then its times to meet your eye doctor for further check up. An Eye specialist gives you all essential medical help for the good being of your eyes. There is a team of all eye specialists like Ophthalmologists, ophthalmic medical practitioner, optometrist, orthoptist, ocularist etc.
Ophthalmology is a branch of medicine that deals with the diseases and surgery of the visual pathways, including the eye, hair, and areas surrounding the eye, such as the lachrymal system and eyelids.

An ophthalmologist is an eye specialist for medical and surgical problems.

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Study examines drug regimen for the treatment of non-small cell lung cancer among older patients

Study examines drug regimen for the treatment of non-small cell lung cancer among older patients [ Back to EurekAlert! ] Public release date: 17-Apr-2012
[ | E-mail | Share Share ]

Contact: Anne Doerr
anne_doerr@dfci.harvard.edu
617-632-5665
JAMA and Archives Journals

WASHINGTON, D.C. Analysis of a drug regimen approved by the F.D.A. in 2006 for the treatment of non-small cell lung cancer (bevacizumab added to the standard chemotherapy regimen carboplatin and paclitaxel) finds Medicare insured patients age 65 years and older who received this regimen did not have improved survival compared to patients who received the standard treatment of carboplatin and paclitaxel alone, according to a study in the April 18 issue of JAMA, a theme issue on comparative effectiveness research.

Deborah Schrag, M.D., M.P.H., of the Dana-Farber Cancer Institute, Boston, presented the findings of the study at a JAMA media briefing at the National Press Club.

"A previous randomized trial demonstrated that adding bevacizumab to carboplatin and paclitaxel improved survival in advanced non-small cell lung cancer (NSCLC). However, longer survival was not observed in the subgroup of patients aged 65 years or older, " according to background information in the article. "Notwithstanding the uncertainty about benefits in the population aged 65 years or older, the Centers for Medicare & Medicaid Services (CMS) has covered bevacizumab therapy for its enrollees subsequent to Food and Drug Administration [FDA] approval. Little is known about how clinicians have interpreted efficacy studies to formulate treatment recommendations, and given that approximately two-thirds of patients with lung cancer receive their diagnoses at age 65 years or older, establishing the survival advantage of bevacizumab in the Medicare population is a priority for informed decision making."

Dr. Schrag and colleagues conducted a study to examine whether adding bevacizumab to carboplatin-paclitaxel was associated with improved survival in the Medicare population. The researchers used analytic strategies to address confounding (factors that can influence outcomes) and selection bias caused by the lack of treatment randomization in observational studies that may limit the ability to make valid inferences about causality. The study included 4,168 Medicare beneficiaries ages 65 years or older with advanced (stage IIIB or stage IV) non-squamous cell NSCLC diagnosed in 2002-2007. Patients were categorized into 3 cohorts based on diagnosis year and type of initial chemotherapy administered within 4 months of diagnosis: (1) diagnosis in 2006-2007 and bevacizumab-carboplatin-paclitaxel therapy; (2) diagnosis in 2006-2007 and carboplatin-paclitaxel therapy; or (3) diagnosis in 2002-2005 and carboplatin-paclitaxel therapy. The associations between carboplatin-paclitaxel with vs. without bevacizumab and overall survival were compared using various models and analyses.

The researchers found that the median (midpoint) overall survival was 9.7 months for patients receiving the bevacizumab combination compared with 8.9 months for those receiving carboplatin-paclitaxel in 2006-2007, and 8.0 months for those receiving carboplatin-paclitaxel in 2002-2005. The 1-year survival probabilities were 39.6 percent for bevacizumab-carboplatin-paclitaxel vs. 40.1 percent for carboplatin-paclitaxel in 2006-2007 and 35.6 percent for carboplatin-paclitaxel in 2002-2005. Controlling for demographic and clinical characteristics in adjusted models, the authors did not find a significant difference in overall survival between patients treated with bevacizumab and those treated only with carboplatin-paclitaxel in either 2006-2007 or 2002-2005.

None of the 4 propensity score-adjusted models demonstrated any evidence to support the superiority of bevacizumab-carboplatin-paclitaxel to carboplatin-paclitaxel. Also, neither subgroup nor sensitivity analyses changed their finding that bevacizumab was not associated with a survival advantage.

"In the future, for malignancies like NSCLC that disproportionately affect elderly patients or where the CMS covers a large proportion of treatment costs, negotiations with pharmaceutical sponsors of pivotal trials might mandate adequate representation of elderly patients and/or preplanned subgroup analyses relevant to the Medicare population. Absent this information, clinicians will need to rely on efficacy data from subgroup analysis of randomized trials, observational data such as this report, and their clinical judgment to make treatment recommendations. Given that neither subgroup analyses from efficacy studies nor observational data analyses identify a benefit for adding bevacizumab to standard carboplatin-paclitaxel therapy, bevacizumab should not be considered standard of care in this context. Clinicians should exercise caution in making treatment recommendations and should use bevacizumab judiciously for their older patients," the authors conclude.

###

(JAMA. 2012;307[15]:1593-1601. Available pre-embargo to the media at www.jamamedia.org)

Editor's Note: Project support was obtained from the Agency for Healthcare Research and Quality (AHRQ) as part of the Developing Evidence to Inform Decisions about Effectiveness (DEcIDE) program and from the National Cancer Institute. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

To contact Deborah Schrag, M.D., M.P.H., call Anne Doerr at 617-632-5665 or email anne_doerr@dfci.harvard.edu.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Study examines drug regimen for the treatment of non-small cell lung cancer among older patients [ Back to EurekAlert! ] Public release date: 17-Apr-2012
[ | E-mail | Share Share ]

Contact: Anne Doerr
anne_doerr@dfci.harvard.edu
617-632-5665
JAMA and Archives Journals

WASHINGTON, D.C. Analysis of a drug regimen approved by the F.D.A. in 2006 for the treatment of non-small cell lung cancer (bevacizumab added to the standard chemotherapy regimen carboplatin and paclitaxel) finds Medicare insured patients age 65 years and older who received this regimen did not have improved survival compared to patients who received the standard treatment of carboplatin and paclitaxel alone, according to a study in the April 18 issue of JAMA, a theme issue on comparative effectiveness research.

Deborah Schrag, M.D., M.P.H., of the Dana-Farber Cancer Institute, Boston, presented the findings of the study at a JAMA media briefing at the National Press Club.

"A previous randomized trial demonstrated that adding bevacizumab to carboplatin and paclitaxel improved survival in advanced non-small cell lung cancer (NSCLC). However, longer survival was not observed in the subgroup of patients aged 65 years or older, " according to background information in the article. "Notwithstanding the uncertainty about benefits in the population aged 65 years or older, the Centers for Medicare & Medicaid Services (CMS) has covered bevacizumab therapy for its enrollees subsequent to Food and Drug Administration [FDA] approval. Little is known about how clinicians have interpreted efficacy studies to formulate treatment recommendations, and given that approximately two-thirds of patients with lung cancer receive their diagnoses at age 65 years or older, establishing the survival advantage of bevacizumab in the Medicare population is a priority for informed decision making."

Dr. Schrag and colleagues conducted a study to examine whether adding bevacizumab to carboplatin-paclitaxel was associated with improved survival in the Medicare population. The researchers used analytic strategies to address confounding (factors that can influence outcomes) and selection bias caused by the lack of treatment randomization in observational studies that may limit the ability to make valid inferences about causality. The study included 4,168 Medicare beneficiaries ages 65 years or older with advanced (stage IIIB or stage IV) non-squamous cell NSCLC diagnosed in 2002-2007. Patients were categorized into 3 cohorts based on diagnosis year and type of initial chemotherapy administered within 4 months of diagnosis: (1) diagnosis in 2006-2007 and bevacizumab-carboplatin-paclitaxel therapy; (2) diagnosis in 2006-2007 and carboplatin-paclitaxel therapy; or (3) diagnosis in 2002-2005 and carboplatin-paclitaxel therapy. The associations between carboplatin-paclitaxel with vs. without bevacizumab and overall survival were compared using various models and analyses.

The researchers found that the median (midpoint) overall survival was 9.7 months for patients receiving the bevacizumab combination compared with 8.9 months for those receiving carboplatin-paclitaxel in 2006-2007, and 8.0 months for those receiving carboplatin-paclitaxel in 2002-2005. The 1-year survival probabilities were 39.6 percent for bevacizumab-carboplatin-paclitaxel vs. 40.1 percent for carboplatin-paclitaxel in 2006-2007 and 35.6 percent for carboplatin-paclitaxel in 2002-2005. Controlling for demographic and clinical characteristics in adjusted models, the authors did not find a significant difference in overall survival between patients treated with bevacizumab and those treated only with carboplatin-paclitaxel in either 2006-2007 or 2002-2005.

None of the 4 propensity score-adjusted models demonstrated any evidence to support the superiority of bevacizumab-carboplatin-paclitaxel to carboplatin-paclitaxel. Also, neither subgroup nor sensitivity analyses changed their finding that bevacizumab was not associated with a survival advantage.

"In the future, for malignancies like NSCLC that disproportionately affect elderly patients or where the CMS covers a large proportion of treatment costs, negotiations with pharmaceutical sponsors of pivotal trials might mandate adequate representation of elderly patients and/or preplanned subgroup analyses relevant to the Medicare population. Absent this information, clinicians will need to rely on efficacy data from subgroup analysis of randomized trials, observational data such as this report, and their clinical judgment to make treatment recommendations. Given that neither subgroup analyses from efficacy studies nor observational data analyses identify a benefit for adding bevacizumab to standard carboplatin-paclitaxel therapy, bevacizumab should not be considered standard of care in this context. Clinicians should exercise caution in making treatment recommendations and should use bevacizumab judiciously for their older patients," the authors conclude.

###

(JAMA. 2012;307[15]:1593-1601. Available pre-embargo to the media at www.jamamedia.org)

Editor's Note: Project support was obtained from the Agency for Healthcare Research and Quality (AHRQ) as part of the Developing Evidence to Inform Decisions about Effectiveness (DEcIDE) program and from the National Cancer Institute. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

To contact Deborah Schrag, M.D., M.P.H., call Anne Doerr at 617-632-5665 or email anne_doerr@dfci.harvard.edu.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


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